Vitiligo: Etiological Study

Abstract

Vitiligo is an acquired pigmentary disorder of the skin that is characterized by circumscribed,
depigmented macules and patches. Has an estimated prevalence of 0.5–2% of the population
worldwide The condition is frequently associated with disorders of autoimmune origin and
hereditary susceptibility in vitiligo patients may refer to proteins that are shown by melanin cells
that are autoantigens that target melanin cells to destroy by the immune system.
This review summarizes the current knowledge on vitiligo and attempts to give an overview
of biochemical, immunogenic and genes that responsible or that may be candidates for the events
of the Vitiligo disease.