Study the role of inhibin b, TPO antibody, and thyroid hormones in patients with hyper and hypothyroidisim

Abstract

The experiment began on September 3, 2023, and continued until August 2, 2024, during which 90 cases of thyroid patients aged 15-90 years were obtained. All studied cases were examined by specialist doctors in the lobbies and laboratories of Tikrit General Hospital, relying on the necessary laboratory tests. The levels of Triiodothyronine (T3), Thyroxine (T4),and thyroid-stimulating hormone (TSH),  were used as a criterion for diagnosing patients with hyperthyroidism and hypothyroidism. Hypothyroidism. The experiment samples were classified into three groups. The first is the healthy group consisted of 20 people, second group (patients), consisted of 35 sick people after confirming that they suffer from hypothyroidism. Third group of patients consisted of 35 sick people after it was confirmed that they had hyperthyroidism. The results of present study show levels of TSH had a significant differences (P>0.05) in the three different groups, for hypothyroid patients at a rate of 15.700 ± (5.270), in hyperthyroid patients at a rate of 0.275 ± (0.194) compared to healthy individuals at a rate of 2.402 ± (0.943), T3 levels showed significant differences (P>0.05) in the three different groups, hypothyroidism patients at a rate of 15.354) ± (3.497), hyperthyroidism patients at a rate of 22.401) ± (1.959) compared to healthy people at a rate of 18.336) ± (1.011), The results of T4 showed significant differences (P>0.05) in the three different groups, hypothyroidism patients at a rate of 15.354) ± (3.497), hyperthyroidism patients at a rate of 22.401) ± (1.959) compared to healthy people at a rate of 18.336) ± (1.011, inhibin b showed significant differences (P>0.05) in the three different groups, hypothyroidism patients was 448.23 (± 29.33), for hyperthyroidism patients was 660.50 (± 38.50) compared to healthy subjects was 531.76 (± 22.75), The TPO results showed significant differences (P>0.05) in the three different groups, for hypothyroidism patients was 3913 ± (454.7). for hyperthyroidism patients was 4907 ± (300.8) compared to healthy individuals was 2905 ± (214.0), The Tg results showed significant differences (P>0.05) in the three different groups, for hypothyroidism patients was 4073.0 ± 318.0, for hyperthyroidism patients was 3337.3 ± 279.8 compared to healthy subjects was 2737.9 ± 211.0.