Phenotypic Analysis and Antibiogram of Oral Infections-Causing Bacteria Isolated from Dental Patients
DOI:
https://doi.org/10.31185/wjps.509Keywords:
Oral infections, oral Streptococci spp., multidrug resistant strainAbstract
Oral infections are commonly observed in individuals and frequently result in enduring inflammatory
states that impact the teeth, such as caries, the gingival tissues surrounding the teeth, including gingivitis and
endodontic lesions, as well as the structures that provide support to the teeth, such as periodontitis. A total of 100
clinical samples were collected from patients with various oral infections. The individuals in the study encompassed
a wide range of ages, ranged from 9 to 70 years, over the timeframe between October 2023 and December 2023. Fifty
pathogenic bacterial strains were obtained from specimens of clinical origin, with the genus Streptococcus accounting
for 27 of these isolates, representing 54% of the total, the highest proportion observed among all specie. The
specimens were identified through the examination of cultural and microscopic features, in addition to being
confirmed using the Vitek2 system for species-level diagnosis. The multidrug-resistant isolates exhibited resistance
to various antibiotics including Erythromycin (100%) classified under the Macrolide group, Cefotaxime (100%),
Cefepime (100%), Ceftriaxone (100%), and Penicillin (96.29%) which falls under the βeta-Lactam category.
Additionally, resistance was also observed against Clindamycin (92.59%) which is categorized as a Lincosamide
antibiotic. In the susceptibility testing of antibiotics, Augmentin demonstrated the highest level of activity among the
tested molecules, thereby affirming its overall efficacy against oral streptococci. Additionally, Trimethoprimsulfamethoxazole and Ampicillin exhibited favorable activity, while Vancomycin also demonstrated effectiveness
against oral streptococci.
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